Nisha D’Silva, BDS, MSD, PhD is the Donald Kerr Endowed Collegiate Professor at the University of Michigan School of Dentistry. She is also Professor of Pathology at the University of Michigan Medical School and a member of the University of Michigan Rogel Cancer Center. Dr. D’Silva is a clinician-scientist; her translational research in head and neck cancer focuses on biomarkers and molecular mechanisms of tumor progression and treatment resistance. She has been the principal investigator of National Institutes of Health (NIH) grants and is currently funded by the National Institute of Dental and Craniofacial Research/NIH Sustaining Outstanding Achievement in Research award. She received the Distinguished Scientist Award for Oral Medicine and Pathology Research from the International Association of Dental Research, and the Rod Cawson Prize from the International Association of Oral Pathologists and the Royal College of Physicians and Surgeons of Glasgow. She is a Fellow of the American Association of Dental Research. Dr. D’Silva is a Diplomate of the American Board of Oral and Maxillofacial Pathology, which is her area of clinical practice. She enjoys teaching and mentoring and is a recipient of university and national mentorship awards.
The keynote speaker presentation title is "Oral Cancer: Subverting the Microenvironment." Head and neck squamous cell carcinoma (HNSCC) is the 6th most common cancer in the world, with about 600,000 new cases diagnosed each year. Invasion is a critical phenotype for development and progression of HNSCC. Elucidation of the mechanisms of invasion could provide novel treatment strategies for HNSCC. Mechanistic studies in HNSCC and the clinical relevance of these findings will be discussed.