Oral Health Research Institute

We’ve helped to improve oral health for half a century

Founded from the successful creation of the world’s first fluoride toothpaste, the Oral Health Research Institute at Indiana University School of Dentistry is a globally recognized center for preventive dentistry research and product testing. Our clinical and laboratory research cores support a wide range of studies, including caries and erosion preventive agents, anti-plaque and anti-gingivitis agents, anti-calculus agents, stain prevention and removal agents, and whitening/bleaching agents.

Beginning with the development of Crest toothpaste, we have an impressive portfolio of clinical trials and testing capabilities that have contributed significantly to improvements in dental health in the United States and beyond.